Oral thrush, also called oral candidiasis, is an infection of the mouth and throat caused by yeasts, most commonly Candida albicans. The inner surfaces of the cheeks and lips are often affected, and sometimes the tongue and the palate. The time between exposure and symptom onset is not precisely known because these yeasts can also be present on healthy skin.
Whether an infection develops depends on the immune system's ability to control excessive yeast growth. The yeasts take advantage of a weakened immune defence to multiply. That is why oral thrush frequently occurs in newborns and infants, whose immune systems are not yet fully developed. During breastfeeding, moisture and warmth under breast pads can also lead to a yeast infection of the mother's nipples. This infection can then be passed to the baby and appear in the infant's mouth as oral thrush.
But older children and adults can also develop oral thrush, especially if their immune defences are weakened by certain medications or conditions such as diabetes mellitus or HIV. Antibiotics and corticosteroids are examples of medicines after which oral thrush may occasionally occur. Older people who have no teeth or who wear dentures are also at risk. Injuries in the mouth, smoking, inadequate oral hygiene, nutrient deficiencies and certain illnesses can also contribute to the development of oral thrush. Reduced saliva production is another risk factor. Acute infectious diseases such as pneumonia can also increase the risk.
Here are some signs that may indicate such an infection. Oral thrush is characterised by white or yellowish spots or coatings on the tongue, the palate, the inside of the cheeks or the gums. The affected areas may also be red and inflamed. Touch, food and drinks can cause pain.
A fungal infection can cause cracks or fissures at the corners of the mouth, known as angular cheilitis. Oral thrush can lead to an unpleasant taste or even a complete loss of taste. The sense of taste usually returns to normal after successful treatment. In severe cases the infection can spread to the throat and oesophagus and cause difficulty swallowing.
There are three types of oral thrush: pseudomembranous candidiasis, acute erythematous candidiasis and hyperplastic candidiasis. Typical for pseudomembranous candidiasis is marked redness of the oral mucosa covered with small white spots. These spots, often found on the inside of the cheeks and lips, on the palate and under the tongue, initially look like milky-white speckles. Sometimes, especially when the yeasts settle under a denture, the gums may also be affected.
Small white deposits can usually be wiped away easily, revealing a red, shiny surface underneath. Over time the spots increase in number and size and may merge into larger white patches. The underlying tissue may bleed slightly when the coating is removed. Oral thrush may also be accompanied by increased thirst, taste disturbances and a furry or cottony feeling in the mouth.
Redness of the mucosa and a burning sensation in the mouth, particularly on the dorsum of the tongue, characterise acute erythematous candidiasis. This form is often seen during antibiotic therapy or in HIV infection and frequently follows pseudomembranous candidiasis. Chronic hyperplastic candidiasis, also called Candida leukoplakia, is characterised by firm white patches with red borders on the mucosa and tongue that are difficult to remove. This form occurs more often in people with weakened immune systems and can persist for months or years.
Oral thrush usually does not have serious health consequences, but it can cause considerable discomfort. Difficulty swallowing and speech problems can occur if the fungus spreads from the mouth to the oesophagus. Together with other symptoms this can lead to eating problems and weight loss. If the immune defence is severely weakened, the yeasts can also invade deeper tissue layers, reach the bloodstream and even cause a life-threatening bloodstream infection (sepsis).
An inconspicuous fungus that normally poses no danger can spread freely when the immune defence is weakened and infect the mucous membranes throughout the mouth. But with these tips and tricks, annoying oral thrush doesn't stand a chance!